KEGG   Homo sapiens (human): 2153
Entry
2153              CDS       T01001                                 
Symbol
F5, FVL, PCCF, RPRGL1, THPH2
Name
(RefSeq) coagulation factor V
  KO
K03902  coagulation factor V (labile factor)
Organism
hsa  Homo sapiens (human)
Pathway
hsa04610  Complement and coagulation cascades
Network
nt06514  Coagulation cascade
  Element
N01511  Common pathway of coagulation cascade, F5 activation
Disease
H00220  Factor V deficiency
H00223  Inherited thrombophilia
H01433  Budd-Chiari syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    2153 (F5)
SSDB
Motif
Pfam: F5_F8_type_C Cu-oxidase_3 Cu-oxidase_2 LSPR
Other DBs
NCBI-GeneID: 2153
NCBI-ProteinID: NP_000121
OMIM: 612309
HGNC: 3542
Ensembl: ENSG00000198734
CPD: C03780
UniProt: P12259
Structure
Position
1:complement(169511951..169586481)
AA seq 2224 aa
MFPGCPRLWVLVVLGTSWVGWGSQGTEAAQLRQFYVAAQGISWSYRPEPTNSSLNLSVTS
FKKIVYREYEPYFKKEKPQSTISGLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYS
KLSEGASYLDHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIE
DFNSGLIGPLLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKSWSQSSSLMYTVNGYVNG
TMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLEQNHHKVSAITLVSATSTTANMTV
GPEGKWIISSLTPKHLQAGMQAYIDIKNCPKKTRNLKKITREQRRHMKRWEYFIAAEEVI
WDYAPVIPANMDKKYRSQHLDNFSNQIGKHYKKVMYTQYEDESFTKHTVNPNMKEDGILG
PIIRAQVRDTLKIVFKNMASRPYSIYPHGVTFSPYEDEVNSSFTSGRNNTMIRAVQPGET
YTYKWNILEFDEPTENDAQCLTRPYYSDVDIMRDIASGLIGLLLICKSRSLDRRGIQRAA
DIEQQAVFAVFDENKSWYLEDNINKFCENPDEVKRDDPKFYESNIMSTINGYVPESITTL
GFCFDDTVQWHFCSVGTQNEILTIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGT
WMLTSMNSSPRSKKLRLKFRDVKCIPDDDEDSYEIFEPPESTVMATRKMHDRLEPEDEES
DADYDYQNRLAAALGIRSFRNSSLNQEEEEFNLTALALENGTEFVSSNTDIIVGSNYSSP
SNISKFTVNNLAEPQKAPSHQQATTAGSPLRHLIGKNSVLNSSTAEHSSPYSEDPIEDPL
QPDVTGIRLLSLGAGEFKSQEHAKHKGPKVERDQAAKHRFSWMKLLAHKVGRHLSQDTGS
PSGMRPWEDLPSQDTGSPSRMRPWKDPPSDLLLLKQSNSSKILVGRWHLASEKGSYEIIQ
DTDEDTAVNNWLISPQNASRAWGESTPLANKPGKQSGHPKFPRVRHKSLQVRQDGGKSRL
KKSQFLIKTRKKKKEKHTHHAPLSPRTFHPLRSEAYNTFSERRLKHSLVLHKSNETSLPT
DLNQTLPSMDFGWIASLPDHNQNSSNDTGQASCPPGLYQTVPPEEHYQTFPIQDPDQMHS
TSDPSHRSSSPELSEMLEYDRSHKSFPTDISQMSPSSEHEVWQTVISPDLSQVTLSPELS
QTNLSPDLSHTTLSPELIQRNLSPALGQMPISPDLSHTTLSPDLSHTTLSLDLSQTNLSP
ELSQTNLSPALGQMPLSPDLSHTTLSLDFSQTNLSPELSHMTLSPELSQTNLSPALGQMP
ISPDLSHTTLSLDFSQTNLSPELSQTNLSPALGQMPLSPDPSHTTLSLDLSQTNLSPELS
QTNLSPDLSEMPLFADLSQIPLTPDLDQMTLSPDLGETDLSPNFGQMSLSPDLSQVTLSP
DISDTTLLPDLSQISPPPDLDQIFYPSESSQSLLLQEFNESFPYPDLGQMPSPSSPTLND
TFLSKEFNPLVIVGLSKDGTDYIEIIPKEEVQSSEDDYAEIDYVPYDDPYKTDVRTNINS
SRDPDNIAAWYLRSNNGNRRNYYIAAEEISWDYSEFVQRETDIEDSDDIPEDTTYKKVVF
RKYLDSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKS
SEGKTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDI
HSGLIGPLLICQKGILHKDSNMPMDMREFVLLFMTFDEKKSWYYEKKSRSSWRLTSSEMK
KSHEFHAINGMIYSLPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLENGNKQHQLG
VWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDRDCRMPMGLSTGIISD
SQIKASEFLGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQG
AKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPIVARY
IRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGDYWEPFR
ARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQ
GVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALRLELFG
CDIY
NT seq 6675 nt   +upstreamnt  +downstreamnt
atgttcccaggctgcccacgcctctgggtcctggtggtcttgggcaccagctgggtaggc
tgggggagccaagggacagaagcggcacagctaaggcagttctacgtggctgctcagggc
atcagttggagctaccgacctgagcccacaaactcaagtttgaatctttctgtaacttcc
tttaagaaaattgtctacagagagtatgaaccatattttaagaaagaaaaaccacaatct
accatttcaggacttcttgggcctactttatatgctgaagtcggagacatcataaaagtt
cactttaaaaataaggcagataagcccttgagcatccatcctcaaggaattaggtacagt
aaattatcagaaggtgcttcttaccttgaccacacattccctgcggagaagatggacgac
gctgtggctccaggccgagaatacacctatgaatggagtatcagtgaggacagtggaccc
acccatgatgaccctccatgcctcacacacatctattactcccatgaaaatctgatcgag
gatttcaactcggggctgattgggcccctgcttatctgtaaaaaagggaccctaactgag
ggtgggacacagaagacgtttgacaagcaaatcgtgctactatttgctgtgtttgatgaa
agcaagagctggagccagtcatcatccctaatgtacacagtcaatggatatgtgaatggg
acaatgccagatataacagtttgtgcccatgaccacatcagctggcatctgctgggaatg
agctcggggccagaattattctccattcatttcaacggccaggtcctggagcagaaccat
cataaggtctcagccatcacccttgtcagtgctacatccactaccgcaaatatgactgtg
ggcccagagggaaagtggatcatatcttctctcaccccaaaacatttgcaagctgggatg
caggcttacattgacattaaaaactgcccaaagaaaaccaggaatcttaagaaaataact
cgtgagcagaggcggcacatgaagaggtgggaatacttcattgctgcagaggaagtcatt
tgggactatgcacctgtaataccagcgaatatggacaaaaaatacaggtctcagcatttg
gataatttctcaaaccaaattggaaaacattataagaaagttatgtacacacagtacgaa
gatgagtccttcaccaaacatacagtgaatcccaatatgaaagaagatgggattttgggt
cctattatcagagcccaggtcagagacacactcaaaatcgtgttcaaaaatatggccagc
cgcccctatagcatttaccctcatggagtgaccttctcgccttatgaagatgaagtcaac
tcttctttcacctcaggcaggaacaacaccatgatcagagcagttcaaccaggggaaacc
tatacttataagtggaacatcttagagtttgatgaacccacagaaaatgatgcccagtgc
ttaacaagaccatactacagtgacgtggacatcatgagagacatcgcctctgggctaata
ggactacttctaatctgtaagagcagatccctggacaggcgaggaatacagagggcagca
gacatcgaacagcaggctgtgtttgctgtgtttgatgagaacaaaagctggtaccttgag
gacaacatcaacaagttttgtgaaaatcctgatgaggtgaaacgtgatgaccccaagttt
tatgaatcaaacatcatgagcactatcaatggctatgtgcctgagagcataactactctt
ggattctgctttgatgacactgtccagtggcacttctgtagtgtggggacccagaatgaa
attttgaccatccacttcactgggcactcattcatctatggaaagaggcatgaggacacc
ttgaccctcttccccatgcgtggagaatctgtgacggtcacaatggataatgttggaact
tggatgttaacttccatgaattctagtccaagaagcaaaaagctgaggctgaaattcagg
gatgttaaatgtatcccagatgatgatgaagactcatatgagatttttgaacctccagaa
tctacagtcatggctacacggaaaatgcatgatcgtttagaacctgaagatgaagagagt
gatgctgactatgattaccagaacagactggctgcagcattaggaatcaggtcattccga
aactcatcattgaatcaggaagaagaagagttcaatcttactgccctagctctggagaat
ggcactgaattcgtttcttcaaacacagatataattgttggttcaaattattcttcccca
agtaatattagtaagttcactgtcaataaccttgcagaacctcagaaagccccttctcac
caacaagccaccacagctggttccccactgagacacctcattggcaagaactcagttctc
aattcttccacagcagagcattccagcccatattctgaagaccctatagaggatcctcta
cagccagatgtcacagggatacgtctactttcacttggtgctggagaattcaaaagtcaa
gaacatgctaagcataagggacccaaggtagaaagagatcaagcagcaaagcacaggttc
tcctggatgaaattactagcacataaagttgggagacacctaagccaagacactggttct
ccttccggaatgaggccctgggaggaccttcctagccaagacactggttctccttccaga
atgaggccctggaaggaccctcctagtgatctgttactcttaaaacaaagtaactcatct
aagattttggttgggagatggcatttggcttctgagaaaggtagctatgaaataatccaa
gatactgatgaagacacagctgttaacaattggctgatcagcccccagaatgcctcacgt
gcttggggagaaagcacccctcttgccaacaagcctggaaagcagagtggccacccaaag
tttcctagagttagacataaatctctacaagtaagacaggatggaggaaagagtagactg
aagaaaagccagtttctcattaagacacgaaaaaagaaaaaagagaagcacacacaccat
gctcctttatctccgaggacctttcaccctctaagaagtgaagcctacaacacattttca
gaaagaagacttaagcattcgttggtgcttcataaatccaatgaaacatctcttcccaca
gacctcaatcagacattgccctctatggattttggctggatagcctcacttcctgaccat
aatcagaattcctcaaatgacactggtcaggcaagctgtcctccaggtctttatcagaca
gtgcccccagaggaacactatcaaacattccccattcaagaccctgatcaaatgcactct
acttcagaccccagtcacagatcctcttctccagagctcagtgaaatgcttgagtatgac
cgaagtcacaagtccttccccacagatataagtcaaatgtccccttcctcagaacatgaa
gtctggcagacagtcatctctccagacctcagccaggtgaccctctctccagaactcagc
cagacaaacctctctccagacctcagccacacgactctctctccagaactcattcagaga
aacctttccccagccctcggtcagatgcccatttctccagacctcagccatacaaccctt
tctccagacctcagccatacaaccctttctttagacctcagccagacaaacctctctcca
gaactcagtcagacaaacctttctccagccctcggtcagatgcccctttctccagacctc
agccatacaaccctttctctagacttcagccagacaaacctctctccagaactcagccat
atgactctctctccagaactcagtcagacaaacctttccccagccctcggtcagatgccc
atttctccagacctcagccatacaaccctttctctagacttcagccagacaaacctctct
ccagaactcagtcaaacaaacctttccccagccctcggtcagatgcccctttctccagac
cccagccatacaaccctttctctagacctcagccagacaaacctctctccagaactcagt
cagacaaacctttccccagacctcagtgagatgcccctctttgcagatctcagtcaaatt
ccccttaccccagacctcgaccagatgacactttctccagaccttggtgagacagatctt
tccccaaactttggtcagatgtccctttccccagacctcagccaggtgactctctctcca
gacatcagtgacaccacccttctcccggatctcagccagatatcacctcctccagacctt
gatcagatattctacccttctgaatctagtcagtcattgcttcttcaagaatttaatgag
tcttttccttatccagaccttggtcagatgccatctccttcatctcctactctcaatgat
acttttctatcaaaggaatttaatccactggttatagtgggcctcagtaaagatggtaca
gattacattgagatcattccaaaggaagaggtccagagcagtgaagatgactatgctgaa
attgattatgtgccctatgatgacccctacaaaactgatgttaggacaaacatcaactcc
tccagagatcctgacaacattgcagcatggtacctccgcagcaacaatggaaacagaaga
aattattacattgctgctgaagaaatatcctgggattattcagaatttgtacaaagggaa
acagatattgaagactctgatgatattccagaagataccacatataagaaagtagttttt
cgaaagtacctcgacagcacttttaccaaacgtgatcctcgaggggagtatgaagagcat
ctcggaattcttggtcctattatcagagctgaagtggatgatgttatccaagttcgtttt
aaaaatttagcatccagaccgtattctctacatgcccatggactttcctatgaaaaatca
tcagagggaaagacttatgaagatgactctcctgaatggtttaaggaagataatgctgtt
cagccaaatagcagttatacctacgtatggcatgccactgagcgatcagggccagaaagt
cctggctctgcctgtcgggcttgggcctactactcagctgtgaacccagaaaaagatatt
cactcaggcttgataggtcccctcctaatctgccaaaaaggaatactacataaggacagc
aacatgcctatggacatgagagaatttgtcttactatttatgacctttgatgaaaagaag
agctggtactatgaaaagaagtcccgaagttcttggagactcacatcctcagaaatgaaa
aaatcccatgagtttcacgccattaatgggatgatctacagcttgcctggcctgaaaatg
tatgagcaagagtgggtgaggttacacctgctgaacataggcggctcccaagacattcac
gtggttcactttcacggccagaccttgctggaaaatggcaataaacagcaccagttaggg
gtctggccccttctgcctggttcatttaaaactcttgaaatgaaggcatcaaaacctggc
tggtggctcctaaacacagaggttggagaaaaccagagagcagggatgcaaacgccattt
cttatcatggacagagactgtaggatgccaatgggactaagcactggtatcatatctgat
tcacagatcaaggcttcagagtttctgggttactgggagcccagattagcaagattaaac
aatggtggatcttataatgcttggagtgtagaaaaacttgcagcagaatttgcctctaaa
ccttggatccaggtggacatgcaaaaggaagtcataatcacagggatccagacccaaggt
gccaaacactacctgaagtcctgctataccacagagttctatgtagcttacagttccaac
cagatcaactggcagatcttcaaagggaacagcacaaggaatgtgatgtattttaatggc
aattcagatgcctctacaataaaagagaatcagtttgacccacctattgtggctagatat
attaggatctctccaactcgagcctataacagacctacccttcgattggaactgcaaggt
tgtgaggtaaatggatgttccacacccctgggtatggaaaatggaaagatagaaaacaag
caaatcacagcttcttcgtttaagaaatcttggtggggagattactgggaacccttccgt
gcccgtctgaatgcccagggacgtgtgaatgcctggcaagccaaggcaaacaacaataag
cagtggctagaaattgatctactcaagatcaagaagataacggcaattataacacagggc
tgcaagtctctgtcctctgaaatgtatgtaaagagctataccatccactacagtgagcag
ggagtggaatggaaaccatacaggctgaaatcctccatggtggacaagatttttgaagga
aatactaataccaaaggacatgtgaagaactttttcaaccccccaatcatttccaggttt
atccgtgtcattcctaaaacatggaatcaaagtattgcacttcgcctggaactctttggc
tgtgatatttactag

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (9)   
   KEGG DISEASE (3)   
   OMIM (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (25)   
   RefSeq(nuc) (1)   
   GenBank (12)   
   EMBL (12)   
3D Structure (13)   
   PDB (13)   
Protein domain (4)   
   Pfam (4)   
All databases (87)   

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